Allostery without conformation change: modelling protein dynamics at multiple scales
نویسندگان
چکیده
منابع مشابه
Allostery without conformation change: modelling protein dynamics at multiple scales.
The original ideas of Cooper and Dryden, that allosteric signalling can be induced between distant binding sites on proteins without any change in mean structural conformation, has proved to be a remarkably prescient insight into the rich structure of protein dynamics. It represents an alternative to the celebrated Monod-Wyman-Changeux mechanism and proposes that modulation of the amplitude of ...
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ژورنال
عنوان ژورنال: Physical Biology
سال: 2013
ISSN: 1478-3967,1478-3975
DOI: 10.1088/1478-3975/10/5/056004